Swanston Street - take any tram to Queensberry Street (Stop 4) and walk down Queensberry Street
Elizabeth Street - take a Route 19 or 59 tram to Haymarket or Queen Victoria Market and walk towards Queensberry Street. Walk along Leicester Street if you're coming from Queen Victoria Market.
You can change from a train to a tram at Melbourne Central Station and take any tram route along Swanston or Elizabeth Street to the destination.
There are demarcated bike lanes around the area, with bike racks available on the street.